Hip implants a bit more likely to fail in women

CHICAGO (AP) — Hip replacements are slightly more likely to fail in women than in men, according to one of the largest studies of its kind in U.S. patients. The risk of the implants failing is low, but women were 29 percent more likely than men to need a repeat surgery within the first three years.

The message for women considering hip replacement surgery remains unclear. It's not known which models of hip implants perform best in women, even though women make up the majority of the more than 400,000 Americans who have full or partial hip replacements each year to ease the pain and loss of mobility caused by arthritis or injuries.

"This is the first step in what has to be a much longer-term research strategy to figure out why women have worse experiences," said Diana Zuckerman, president of the nonprofit National Research Center for Women & Families. "Research in this area could save billions of dollars" and prevent patients from experiencing the pain and inconvenience of surgeries to fix hip implants that go wrong.

Researchers looked at more than 35,000 surgeries at 46 hospitals in the Kaiser Permanente health system. The research, published Monday in JAMA Internal Medicine, was funded by the U.S. Food and Drug Administration.

After an average of three years, 2.3 percent of the women and 1.9 percent of the men had undergone revision surgery to fix a problem with the original hip replacement. Problems included instability, infection, broken bones and loosening.

"There is an increased risk of failure in women compared to men," said lead author Maria Inacio, an epidemiologist at Southern California Permanente Medical Group in San Diego. "This is still a very small number of failures."

Women tend to have smaller joints and bones than men, and so they tend to need smaller artificial hips. Devices with smaller femoral heads — the ball-shaped part of the ball-and-socket joint in an artificial hip — are more likely to dislocate and require a surgical repair.

That explained some, but not all, of the difference between women and men in the study. It's not clear what else may have contributed to the gap. Co-author Dr. Monti Khatod, an orthopedic surgeon in Los Angeles, speculated that one factor may be a greater loss of bone density in women.

The failure of metal-on-metal hips was almost twice as high for women than in men. The once-popular models were promoted by manufacturers as being more durable than standard plastic or ceramic joints, but several high-profile recalls have led to a decrease in their use in recent years.

"Don't be fooled by hype about a new hip product," said Zuckerman, who wrote an accompanying commentary in the medical journal. "I would not choose the latest, greatest hip implant if I were a woman patient. ... At least if it's been for sale for a few years, there's more evidence for how well it's working."

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Online:

Journal: http://www.jamainternalmed.com

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Time to refer Syrian war crimes to ICC: U.N. inquiry

GENEVA (Reuters) - United Nations investigators said on Monday that Syrian leaders they had identified as suspected war criminals should face the International Criminal Court (ICC).

The investigators urged the U.N. Security Council to "act urgently to ensure accountability" for violations, including murder and torture, committed by both sides in an uprising and civil war that has killed about 70,000 people since March 2011.

"Now really it's time ... We have a permanent court, the International Criminal Court, who would be ready to take this case," Carla del Ponte, a former ICC chief prosecutor who joined the U.N. team in September, told a news briefing in Geneva.

But because Syria is not party to the Rome Statute that established the ICC, the only way the court can investigate the situation is if it receives a referral from the Security Council. Russia, Assad's long-standing ally and a permanent veto-wielding member of the council, has opposed such a move.

"We cannot decide. But we pressure the international community to decide because it's time to act," del Ponte said.

Brazilian expert Paulo Pinheiro, who leads the U.N. inquiry set up in 2011, said: "We are in very close dialogue with all the five permanent members and with all the members of the Security Council, but we don't have the key that will open the path to cooperation inside the Security Council."

His team of some two dozen experts is tracing the chain of command in Syria to establish criminal responsibility and build a case for eventual prosecution.

"Of course we were able to identify high-level perpetrators," del Ponte said, adding that these were people "in command responsibility...deciding, organizing, planning and aiding and abetting the commission of crimes".

She said it was urgent for the Hague-based war crimes tribunal to take up cases of "very high officials", but did not identify them, in line with the inquiry's practice.

"We have crimes committed against children, rape and sexual violence. We have grave concerns. That is also one reason why an international body of justice must act because it is terrible."

Del Ponte, who tried former Yugoslav President Slobodan Milosevic at the International Criminal Tribunal for the Former Yugoslavia on war crimes charges, said the ICC prosecutor would need to deepen the investigation on Syria before an indictment could be prepared.

Karen Koning AbuZayd, an American member of the U.N. team, told Reuters it had information pointing to "people who have given instructions and are responsible for government policy, people who are in the leadership of the military, for example".

The inquiry's third roster of suspects, building on lists drawn up in the past year, remains secret. It will be entrusted to U.N. High Commissioner for Human Rights Navi Pillay upon expiry of its mandate at the end of March, the report said.

Pillay, a former ICC judge, said on Saturday Assad should be investigated for war crimes, and called for outside action on Syria, including possible military intervention.

Pinheiro said the investigators would not speak publicly about "numbers, names or levels" of suspects.

SEVEN MASSACRES IDENTIFIED

The investigators' latest report, covering the six months to mid-January, was based on 445 interviews conducted abroad with victims and witnesses, as they have not been allowed into Syria.

"We identified seven massacres during the period, five on the government side, two on the armed opponents' side. We need to enter the sites to be able to confirm elements of proof that we have," del Ponte said.

The U.N. report said the ICC was the appropriate institution for the fight against impunity in Syria. "As an established, broadly supported structure, it could immediately initiate investigations against authors of serious crimes in Syria."

Government forces have carried out shelling and air strikes across Syria including Aleppo, Damascus, Deraa, Homs and Idlib, the 131-page report said, citing corroborating satellite images.

"Government forces and affiliated militias have committed extra-judicial executions, breaching international human rights law. This conduct also constitutes the war crime of murder. Where murder was committed as part of a widespread or systematic attack against a civilian population, with knowledge of that attack, it is a crime against humanity," the report said.

Those forces have targeted bakery queues and funeral processions to spread "terror among the civilian population".

Rebels fighting to topple Assad have also committed war crimes including murder, torture, hostage-taking and using children under age 15 in hostilities, the U.N. report said.

"They continue to endanger the civilian population by positioning military objectives inside civilian areas" and rebel snipers had caused "considerable civilian casualties", it said.

George Sabra, a vice president of the opposition Syrian National Coalition, asked about the U.N. report, told Reuters at a conference in Stockholm: "We condemn all kind of crimes, regardless who did it.

"We can't ignore that some mistakes have been made and maybe still happen right now. But nobody also can ignore that the most criminal file is that of the regime."

(This story has been corrected to fix name of Milosevic tribunal in 11th paragraph)

(Reporting by Stephanie Nebehay; additional reporting by Anna Ringstrom in Stockholm; Editing by Mark Heinrich)

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Greater US military role in Mali likely after polls: senator

BAMAKO: The United States is likely to play a more active military role in Mali, where French-led forces are battling Islamist rebels, after the country holds elections, the chair of a key Senate sub-committee said Monday.

Washington has been providing intelligence, transport and mid-air refuelling to France, which launched its intervention last month, but cannot work directly with the Malian army until a democratically elected government replaces current leaders who came to power after a coup, said Christopher Coons, chair of the Senate foreign relations committee's Africa sub-committee.

"There is the hope that there will be additional support from the United States in these and other areas, but ... American law prohibits direct assistance to the Malian military following the coup," Coons told journalists in the Malian capital.

"After there is a full restoration of democracy, I would think it is likely that we will renew our direct support for the Malian military," added the senator, who led a bipartisan congressional delegation to Mali to meet with interim president Dioncounda Traore and French and African defence officials.

US military aid to Mali before the March 2012 coup consisted largely of training and equipment such as vehicles, a State Department official said.

But military assistance "would obviously be resumed in a way commensurate with the current needs. Priorities would have shifted a bit," the official added.

"There could be other kinds of assistance that had there not been a coup we could have provided, or requests for things now that we can't provide."

Some US lawmakers criticised President Barack Obama's administration last week for not doing more to help France in Mali.

"This is a NATO ally fighting Al-Qaeda-linked terrorists -- it shouldn't be that hard," said House foreign affairs committee chairman Ed Royce.

The hint of greater US involvement after elections adds to the complicated calculus of picking a date for the polls.

Traore, the interim president, has said he wants elections by July 31.

But critics say that is too soon given the problems Mali still faces, including ongoing insurgent attacks, a deeply divided military and hundreds of thousands of people who have fled their homes.

The minister responsible for organising the elections, Territorial Administration Minister Moussa Sinko Coulibaly, said last week the timeline "can be changed if necessary".

France, which launched its intervention on January 11 as Al-Qaeda-linked groups that had occupied the north for 10 months made incursions into government territory, is keen to share the military burden in Mali, and has announced plans to start bringing its 4,000 troops home in March.

The European Union formally approved a military training mission Monday that will be tasked with getting Mali's under-funded army ready to secure reclaimed territory.

But France is the only Western country with combat troops on the ground, and would like to hand over to some 6,000 west African troops who are slowly being deployed to help.

Mali imploded after a coup by soldiers who blamed the government for the army's humiliation at the hands of separatist rebels in the north.

With the capital in disarray, Al-Qaeda-linked fighters hijacked the independence rebellion and took control of a territory larger than Texas.

-AFP/ac

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Britain wants to be India’s partner of choice: UK PM

MUMBAI: British Prime Minister David Cameron is seeking a special relationship between Britain and India, one that goes beyond business.

Kicking off his India visit, Cameron said India will be one of the leading nations in this century and Britain wanted to be its partner of choice. He was speaking at the head office of Hindustan Unilever (HUL), the Indian subsidiary of Unilever, where an announcement was made regarding an investment of 50 million euros (approximately Rs 360 crore) in the Anglo Dutch consumer goods multinational's first Asian aerosol deodorant manufacturing facility in Khamgaon, Maharashtra.

"I want Britain and India to have a very special relationship. India's rise is going to be one of the big phenomena of the century and it is incredibly impressive to see the vibrancy of your democracy, the great strength of the diversity of your country and the enormous power of your economy that is going to be one of the top three economies by 2030. That's why I'm here. Britain wants to be your partner of choice," Cameron said, while addressing HUL employees on Monday morning.

Britain is the biggest European investor in India while India puts half of its investment in Europe into Britain. Stressing on taking the ties between the two countries beyond business, Cameron said Britain would be keen to assist India in setting up universities, on meeting its target of doubling its spend on health as a percentage of its GDP as also in building a corridor between Mumbai and Bangalore.

"We think there are huge ties obviously of history, language, culture and business, but we think we have only just started on this sort of partnership which we could build. Yes, it's a partnership about business but it should go way beyond business. I've brought some of the best businesses here to India, but we have also brought the Premier League, top universities and the British museum. We want to tie up in so many different ways," said Cameron, while adding this is a relationship about the future and not the past.

"As far as I'm concerned, the sky is the limit," he said.

Beyond business, Cameron said it is also about culture and diplomacy. "We both face the challenge of terrorism and we want to meet the challenge of fighting terrorists together," said Cameron.

While Cameron fielded questions from Leverites on topics ranging from sustainability, environment and diversity, Cameron specifically said, "It's great to be visiting Unilever's Indian headquarters today — more than 120 years since Sunlight soap, one of Unilever's earliest products, was first exported from Britain to India. Unilever is a shining example of how a business with British roots can succeed in India and beyond and I'm delighted to hear they're expanding further, investing over £40 million in a new manufacturing plant in Khamgaon to service the emerging Indian and South Asian markets."

"Today's announcement is another example of our commitment to cater to our growth in India. It will enable us to better serve consumers with innovation and green technology, as well as improve service levels to our retail customers," said Nitin Paranjpe, MD & CEO, HUL.

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Nike, Oakley Distance Themselves from Pistorius

Corporate sponsors of Olympic "blade runner" Oscar Pistorius have begun to distance themselves from the sprinter, who is accused of murdering his model girlfriend, Reeva Steenkamp. Pistorius is back to court in South Africa Tuesday morning on murder charges.

Oakley, the eyewear manufacturer, and the sporting goods giant Nike announced today that they would no longer run ads featuring Pistorius, the South African double-amputee who gained worldwide fame for running on carbon-fiber blades.

"In light of the recent allegations, Oakley is suspending its contract with Oscar Pistorius, effective immediately. Our hearts are with the families during this difficult time and we'll continue to follow the developments in this tragic case," Oakley spokeswoman Cheri Quigley said in a statement released this afternoon.

Earlier in the day, Nike said it had "no plans" to use Pistorius in future ad campaigns, according to the Associated Press. Nike had already pulled an Internet ad showing Pistorius starting to sprint with the caption, "I am the bullet in the chamber."

The companies made their announcements shortly after Pistorius' own agent, Peet Van Zyl, said publicly that he expected the sponsors to stick with Pistorius through the legal process.

PHOTOS: Paralympic Champion Charged in Killing

Pistorius will appear in court Tuesday morning for a bail hearing. His attorneys are expected to argue against the charge of premeditated murder.

His family has said the shooting was an accident.

The news comes as more details emerge about the incident on Thursday morning in which Pistorius allegedly shot and killed Steenkamp at his gated home in Pretoria, South Africa.

Bryn Lennon; Gallo Images/Getty Images

Oscar Pistorius Allegedly Fought the Night of Shooting Watch Video

Oscar Pistorius: Possibly Incriminating Information Leaked Watch Video

'Blade Runner' Murder Charges: Family Insist Accidental Shooting Watch Video

News reports in local papers have said that police are investigating whether Pistorius had an anger-management problem that led to the incident. They focused in on a bloodied cricket bat that may have been used when Steenkamp died.

A "shocked" teammate of Oscar Pistorius rebutted the rumors and speculation in South Africa that Pistorius had an anger problem.

Ofentse Mogawane, a sprinter for the South African Olympic team who ran the 400-meter relay with Pistorius in the London summer games last year, said Pistorius had always been genial to him and other people.

Mogawane said he would be in court Tuesday to support his friend.

"Basically, he was a very good guy to us, to the teammates and to most athletes," Mogawane said. "He was a really humble person and I wouldn't say a bad word about him. We never had any kind of clash, never any kind of fight or disagreement or arguing.

"The way Oscar's case was, it shocked me, shocked most of the people who know him. Tomorrow in court I am going to be there to support him. To hear what happened the night of the incident," he said.

"Sometimes when people are angry they cannot control their anger. Something must have happened."

Mogawane, 30, spoke in support of Pistorius after a report in South Africa's City Press newspaper that claimed police were looking into the possibility that a bloody cricket bat found in his bedroom was used before the shooting.

"The way the news has been running around in South Africa, that he is a short-tempered person, a person who has problems with anger management, they just want something to say," Mogawane said. "They don't know Oscar at all. They just want to get interviewed and take pictures. But truly speaking, it's just a lot of speculation."

Mogawane said he had seen Pistorius become angry before, but only in the same way as any other athlete or person.

But the City Press reported Sunday that police are investigating different scenarios involving the bat. Among them is the possibility that the flat-fronted bat was used in a violent argument before the shooting.

The paper also reported that Pistorius might have first shot Steenkamp in the bedroom, and that she possibly fled to the bathroom where she was shot three more times through the door.

When Pistorius' family arrived at the scene before paramedics, they saw him carrying Steenkamp down the stairs and performing mouth-to-mouth resuscitation on her, City Press reported.

Pistorius, who is nicknamed the "blade runner" because of the carbon-fiber blades on which he runs, has canceled all his upcoming racing appearances, his agent said Sunday night.

The decision was made to "allow Oscar to concentrate on the upcoming legal proceedings and to help and support all those involved as they try to come to terms with this very difficult and distressing situation," Van Zyl, of In Site Athlete Management, said in a statement.

Pistorius' father was quoted overnight in the South African paper The Sunday Times saying his countrymen are destroying a national icon.

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Study: Better TV might improve kids' behavior

SEATTLE (AP) — Teaching parents to switch channels from violent shows to educational TV can improve preschoolers' behavior, even without getting them to watch less, a study found.

The results were modest and faded over time, but may hold promise for finding ways to help young children avoid aggressive, violent behavior, the study authors and other doctors said.

"It's not just about turning off the television. It's about changing the channel. What children watch is as important as how much they watch," said lead author Dr. Dimitri Christakis, a pediatrician and researcher at Seattle Children's Research Institute.

The research was to be published online Monday by the journal Pediatrics.

The study involved 565 Seattle parents, who periodically filled out TV-watching diaries and questionnaires measuring their child's behavior.

Half were coached for six months on getting their 3-to-5-year-old kids to watch shows like "Sesame Street" and "Dora the Explorer" rather than more violent programs like "Power Rangers." The results were compared with kids whose parents who got advice on healthy eating instead.

At six months, children in both groups showed improved behavior, but there was a little bit more improvement in the group that was coached on their TV watching.

By one year, there was no meaningful difference between the two groups overall. Low-income boys appeared to get the most short-term benefit.

"That's important because they are at the greatest risk, both for being perpetrators of aggression in real life, but also being victims of aggression," Christakis said.

The study has some flaws. The parents weren't told the purpose of the study, but the authors concede they probably figured it out and that might have affected the results.

Before the study, the children averaged about 1½ hours of TV, video and computer game watching a day, with violent content making up about a quarter of that time. By the end of the study, that increased by up to 10 minutes. Those in the TV coaching group increased their time with positive shows; the healthy eating group watched more violent TV.

Nancy Jensen, who took part with her now 6-year-old daughter, said the study was a wake-up call.

"I didn't realize how much Elizabeth was watching and how much she was watching on her own," she said.

Jensen said her daughter's behavior improved after making changes, and she continues to control what Elizabeth and her 2-year-old brother, Joe, watch. She also decided to replace most of Elizabeth's TV time with games, art and outdoor fun.

During a recent visit to their Seattle home, the children seemed more interested in playing with blocks and running around outside than watching TV.

Another researcher who was not involved in this study but also focuses his work on kids and television commended Christakis for taking a look at the influence of positive TV programs, instead of focusing on the impact of violent TV.

"I think it's fabulous that people are looking on the positive side. Because no one's going to stop watching TV, we have to have viable alternatives for kids," said Dr. Michael Rich, director of the Center on Media and Child Health at Children's Hospital Boston.

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Online:

Pediatrics: http://www.pediatrics.org

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Contact AP Writer Donna Blankinship through Twitter (at)dgblankinship

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Israeli lawmakers to investigate Australian spy mystery

JERUSALEM (Reuters) - Israeli lawmakers announced plans on Sunday to investigate the 2010 jailhouse death of a reported Australian immigrant recruit to the Mossad spy agency.

The statement by Parliament's Foreign Affairs and Defence Committee followed calls by Prime Minister Benjamin Netanyahu at a cabinet meeting to dim a growing media spotlight on the affair he saw as at risk of jeopardizing national security.

The case kept under wraps for two years then publicized by Australian television last Tuesday involves a 34-year-old immigrant, Ben Zygier, said to be a Mossad operative held on suspicion of security offences, who died of what has been labeled an apparent suicide behind bars.

In a terse communique, the legislative panel's subcommittee on intelligence said it has "decided to conduct an intensive examination of all aspects of the incident involving the prisoner found dead in his (prison) cell in December 2010."

While unlikely to have any immediate political consequences the investigation may lead to a wider inquiry with potentially broader repercussions.

Netanyahu's government has restricted reporting in Israel on the case, now overshadowing his victory in a national election held last month, using court gag orders, military censorship and direct requests to news editors.

Such steps have done little to douse demands for the authorities to come clean about the circumstances of Zygier's imprisonment and how he was able to kill himself in a highly-supervised isolation cell.

Without citing the case specifically, Netanyahu said on Sunday he "absolutely trusts" Israel's security services and what he described as the independent legal monitoring system under which they operated.

"We are an exemplary democracy," Netanyahu said in remarks aired by Israeli broadcasters.

"But we are also more threatened, more challenged, and therefore we have to ensure the proper operation of our security branches," Netanyahu also said.

"Therefore I ask over everyone: Let the security services continue working quietly so that we can continue to live in safety and tranquility in the State of Israel."

The few Israeli officials who have spoken of Zygier's case have not denied that he was linked to Mossad, which in early 2010 was accused by Dubai of using Australian passport-holders to assassinate a Palestinian arms procurer in the Gulf emirate.

BETRAYED MOSSAD MISSIONS?

Media reports have speculated that Israel suspected the Melbourne-born Jew of betraying or threatening to divulge Mossad missions, perhaps to Australia's security services, as they probed passport fraud.

Civil liberties groups and some Israeli lawmakers have demanded to know whether Zygier's rights were violated by his months of incarceration under alias.

In an apparent reversal from previous statements, Australian Foreign Minister Bob Carr said on Thursday his ministry had known about Zygier's jailing as early as February 2010. On Wednesday he said Australian diplomats in Israel only found out about the detention after his death in custody later that year.

Avigdor Feldman, an Israeli lawyer with whom Zygier consulted in Ayalon prison, said last week that that meeting was arranged by a "Mossad liaison" and that his client had denied "grave charges" for which he awaited trial.

Feldman also said that Zygier's family, which has declined all comment on the affair, knew about his detention. The incarceration was approved by several Israeli courts.

Two senior cabinet members, Intelligence Minister Dan Meridor and Strategic Affairs Minister Moshe Yaalon, told Israeli media on Saturday the case was rare but lawful.

"There are extreme situations...to do with our security and even the need to preserve human life, when we need to take an extreme step such as this," Yaalon told Channel Two television.

Meridor said that publishing the prisoner's identity would have risked "serious harm to security." He did not elaborate.

Tzachi Hanegbi, a lawmaker from Netanyahu's conservative Likud party said he had never been informed of Zygier's arrest as chairman of the parliamentary defence panel at the time.

"This requires explanation," Hanegbi said. "Usually, every significant subject, whether it is impressive achievements or embarrassing failures, is laid out before the subcommittee."

Former Mossad director Danny Yatom told Reuters the agency was under no legal obligation to brief oversight lawmakers in such circumstances.

(Writing by Allyn Fisher-Ilan and Dan Williams; Editing by Jason Webb)

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Singapore's NODX up 0.5% on-year in January

SINGAPORE: Non-oil domestic exports (NODX) rose by 0.5 per cent on-year in January 2013, compared to the 16.3 per cent decrease in the previous month.

This was due to a rise in non-electronic NODX, which outweighed the decline in electronic NODX.

On a year-on-year basis, electronic NODX contracted by 5.6 per cent in January, after the 19.1 per cent decline in the previous month.

Meanwhile, non-electronic NODX expanded by 3.8 per cent on-year in January, compared to the 14.8 per cent decline in the previous month.

On a month-on-month seasonally adjusted basis, NODX fell 1.8 per cent in January, following the previous month's 4.2 per cent decline. This was attributed to a contraction in non electronic NODX, which outweighed an expansion in electronic NODX.

On a year-on-year basis, NODX to all of the top 10 NODX markets, except the EU 27, the US, Thailand, Hong Kong and South Korea, rose in January 2013. The top three contributors to the NODX rise in January 2013 were China, Taiwan and Japan.

-CNA/ir

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Central staff strength down from 32 lakh to 23 lakh in a decade

NEW DELHI: The central government's cut on plan and non-plan posts over a decade has had an adverse impact on the bureaucracy. In the last 12 years, strength of central staff has come down by nearly 28% -- from 32 lakh in 1999 to almost 23 lakh in 2011, excluding the paramilitary forces.

A recent review carried out during preparation of the Union account 2011-12 shows the cut has been made across all ministries except the ministry of personnel, which regulates manpower (and has less staff to deal with now). Staff strength in the personnel ministry has gone up from 8,200 in 1999 to 8,400 in 2011 and is projected to grow to 10,474 by 2013.

The trend otherwise is similar in all other ministries which have seen 20-30% cut in their manpower over the last decade. Besides the personnel ministry, only the paramilitary forces, under the home ministry, has shown substantial increase -- from 5.74 lakh in 1999 to 9 lakh in 2011. Overall, the number of civilian staff in the central government fell from 31.71 lakh in 1999 to 22.93 lakh in 2011.

With the economy expanding, the cut in government manpower has had a demoralizing impact on the bureaucracy, particularly senior officials who have to work with little support staff at hand to carry out basic file work. The Union account for 2011-12 is likely to be finalized during the budget session of Parliament.

The multitudes of scams being reported also has to do with lack of a monitoring mechanism within the government. The lean bureaucracy struggles to carry out routine policy implementation while monitoring takes last priority.

Other than savings through manpower cut, the government had after the financial meltdown in 2008-09 announced mandatory cut of 10% in non-plan expenditure that included restriction on foreign travels of ministers and official delegations, slashing down expenses on seminars and conferences besides cut in creation of plan and non-plan posts.

The cut on non-plan expenditure is expected to save the government around Rs 1,000 crore, according to a preliminary estimate by the finance ministry.

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Pistorius Case: Agent Cancels All Future Races

Oscar Pistorius won't run in any of the future races that the athlete was contracted to compete in, but the Paraylmpic gold medalist's sponsors are still supportive as he faces a murder charge, his agent said today.

The decision to cancel Pistorius' scheduled appearances was made to "allow Oscar to concentrate on the upcoming legal proceedings and to help and support all those involved as they try to come to terms with this very difficult and distressing situation," Peet Van Zyl of In Site Athlete Management said in a statement.

"I have decided that following these tragic events that we have no option but to cancel all future races that Oscar Pistorius had been contracted to compete in," Van Zyl said.

Pistorius was slated to compete in races in Australia and Brazil, as well as at the Drake Relays in Iowa and the Manchester City Games in the U.K.

Van Zyl also said that Pistorius' sponsors and partners are supportive.

"I can confirm that at this point in time, all parties are supportive and their contractual commitments are maintained. They have said they are happy to let the legal process takes its course before making any change in their position," Van Zyl said in the statement.

However, M-Net movies, a subscription-funded South African television channel has pulled their ad campaign featuring Pistorius, tweeting, "Out of respect & sympathy to the bereaved, M-Net will be pulling its entire Oscar campaign featuring Oscar Pistorius with immediate effect."

The agent's announcement comes as family and friends rallied to Pistorius' defense -- saying they believe the Paralympic gold medalist's story that he shot his model girlfriend Reeva Steenkamp by accident after he mistook her for an intruder.

Adrian Dennis/AFP/Getty Images; Mike Holmes/The Herald/Gallo Images/Getty Images

'Blade Runner' Murder Mystery: Family Speaks Out Watch Video

'Blade Runner' on Suicide Watch After Charged With Girlfriend's Murder Watch Video

Oscar Pistorius Charged in Shooting Death of Girlfriend Watch Video

"When you are a sportsman, you act even more on instinct ... it's instinct -- things happen and that's what you do," Pistorius' father Henke Pistorius, 59, told The Telegraph.

The 26-year-old athlete, known as the "Blade Runner" because of the carbon-fiber blades he runs on, was charged Friday with premeditated murder.

PHOTOS: Paralympic Champion Charged With Murder

If convicted, Pistorius could face at least 25 years in jail.

"All of us saw at firsthand how close [Steenkamp] had become to Oscar during that time and how happy they were. They had plans together and Oscar was happier in his private life than he had been for a long time," Pistorius' uncle Arnold Pistorius said on Saturday.

According to South African newspaper Beeld, Steenkamp was killed nearly two hours after police were called to Pistorius' home to respond to reports of an argument at the complex.

Police said they have responded to disputes at the sprinter's residence before, but did not say whether Steenkamp was involved.

The athlete's best friend said Pistorius called him after the shooting to say "there has been a terrible accident, I shot Reeva," Justin Divaris told the Sunday People.

While his family insists he is not a murderer, prosecutors disagree.

Police sources told local media that Steenkamp was shot through the bathroom door where she may have been trying to hide to save herself.

Reeva Steenkamp

A memorial service for Steenkamp will be held in Port Elizabeth on Tuesday evening, SABC reported. Her body will be flown back for the service before being cremated, her family said.

"Her future has been cut short ... I dare say she's with the angels," said Mike Steenkamp, Reeva Steenkamp's uncle.

The South African reality show Steenkamp competed in premiered Saturday night on SABC as planned and included a special tribute to the slain law school graduate whose modeling career was starting to take off.

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